Vitiligo and medications

Table of contents

Pharmacological treatment against vitiligo is based on corticosteroids or topical immunosuppressive drugs.

Another type of treatment that can be used to cure vitiligo is PUVA therapy.
It is a particular type of therapy which is based on the oral or topical administration of particular photosensitizing substances. These particles called psoralens when the patient is next irradiated with UV at certain wavelengths.
The goal of this treatment is to restore the melanocyte activity previously compromised by the autoimmune response.
Finally, in some cases, the doctor may also consider a possible melanocyte transplant.

Vitiligine e farmaci tipologie

Vitiligo and corticosteroid drugs

Topical corticosteroids are among the drugs of first choice in the treatment of vitiligo.

However, due to the serious side effects they can cause such as:

  • stretch marks
  • thinning of the skin
  • acne

Their use should only take place under the strict supervision of the doctor.

Corticosteroids are anti-inflammatory drugs that can help the skin’s re-pigmentation process.
However, it must be said that their use is usually limited to cases of localized vitiligo.


Betamethasone is available for cutaneous administration in several forms:

  • creams
  • ointments
  • solution
  • skin emulsions
  • gel

Usually, it is recommended to apply the betamethasone-based product for skin use directly on the affected area 1-2 times a day.
In any case, it is imperative to carefully follow the instructions given by your doctor.


Clobetasol is also available in different forms for cutaneous use.
Generally, it is recommended to perform one or two applications of the product a day, directly on the affected area. Again, it is essential to follow the directions given by your doctor.

Vitiligo and immunosuppressive drugs

Topical immunosuppressants can also be used against vitiligo.
These drugs work by suppressing the activity of the immune system. In this way, they decrease the autoimmune response towards melanocytes that characterizes vitiligo.


Tacrolimus is usually used to treat atopic dermatitis. However, this drug can also be used in the therapy against vitiligo.

It is available for topical application in the form of an ointment for skin use. The product must be applied to the skin in a thin layer.
The frequency of administration and the duration of treatment must be determined by the doctor.


Pimecrolimus is also normally used in the treatment of atopic dermatitis, but is also used in the treatment of vitiligo.
It is available in the form of a skin cream that should be applied to the affected area once or twice a day.
Also in this case, the frequency of administration and the duration of treatment must be established by the doctor

Contact us

Our center in Milan employs doctors specialized in Psoriasis, with proven experience. Call us to find out more!

More News
Write to
Dr. Marina Fantato fantato vitiligine

    Blank Form (#5)

    Have you ever received a Vitiligo diagnosis?

    Me: No

    Me: Yes

    Does your family member suffer from Vitiligo or have they ever experienced symptoms compatible with Vitiligo?

    Me: No

    Me: Yes

    Do you have white patches in particular areas such as face, scalp, lower back, elbows, knees, palms, and feet?

    Me: No

    Me: Yes

    Dear user, thank you for completing the questionnaire. Based on your answers, we recommend that you leave your email address to be contacted by one of our experts.

    Dear user, thank you for completing the questionnaire. Based on your answers, he did not reveal any Psoriasis problems. If you believe that your pathology is not well controlled, we recommend that you leave us your email to be contacted by one of our experts.