Pharmacological treatment against vitiligo is based on corticosteroids or topical immunosuppressive drugs.
Another type of treatment that can be used to cure vitiligo is PUVA therapy.
It is a particular type of therapy which is based on the oral or topical administration of particular photosensitizing substances. These particles called psoralens when the patient is next irradiated with UV at certain wavelengths.
The goal of this treatment is to restore the melanocyte activity previously compromised by the autoimmune response.
Finally, in some cases, the doctor may also consider a possible melanocyte transplant.
Vitiligo and corticosteroid drugs
Topical corticosteroids are among the drugs of first choice in the treatment of vitiligo.
However, due to the serious side effects they can cause such as:
- stretch marks
- thinning of the skin
Their use should only take place under the strict supervision of the doctor.
Corticosteroids are anti-inflammatory drugs that can help the skin’s re-pigmentation process.
However, it must be said that their use is usually limited to cases of localized vitiligo.
Betamethasone is available for cutaneous administration in several forms:
- skin emulsions
Usually, it is recommended to apply the betamethasone-based product for skin use directly on the affected area 1-2 times a day.
In any case, it is imperative to carefully follow the instructions given by your doctor.
Clobetasol is also available in different forms for cutaneous use.
Generally, it is recommended to perform one or two applications of the product a day, directly on the affected area. Again, it is essential to follow the directions given by your doctor.
Vitiligo and immunosuppressive drugs
Topical immunosuppressants can also be used against vitiligo.
These drugs work by suppressing the activity of the immune system. In this way, they decrease the autoimmune response towards melanocytes that characterizes vitiligo.
Tacrolimus is usually used to treat atopic dermatitis. However, this drug can also be used in the therapy against vitiligo.
It is available for topical application in the form of an ointment for skin use. The product must be applied to the skin in a thin layer.
The frequency of administration and the duration of treatment must be determined by the doctor.
Pimecrolimus is also normally used in the treatment of atopic dermatitis, but is also used in the treatment of vitiligo.
It is available in the form of a skin cream that should be applied to the affected area once or twice a day.
Also in this case, the frequency of administration and the duration of treatment must be established by the doctor